Project Artichoke

Project ARTICHOKE was a CIA covert program launched in 1951 to develop mind control and advanced interrogation techniques during the Cold War. Evolving from Project BLUEBIRD, it focused on using LSD, hypnosis, mescaline, morphine addiction, and sensory deprivation to induce amnesia, compliance, and involuntary actions—like the “Manchurian Candidate” assassin concept. Subjects included POWs, defectors, CIA agents, and unwitting civilians tested in U.S. safe houses and overseas sites in Japan, Germany, and Southeast Asia. Led by Paul F. Gaynor and the Office of Security, it explored narco-hypnosis, regression therapy, and incapacitating agents. ARTICHOKE directly preceded MKULTRA in 1953. Declassified documents reveal unethical human experiments, raising lasting concerns over consent, brainwashing, and government overreach.

Long Version

Project ARTICHOKE, also known as Operation ARTICHOKE, was a covert operations program initiated by the Central Intelligence Agency (CIA) during the Cold War era to explore advanced interrogation techniques, mind control, and behavior control methods. Launched on August 20, 1951, under the auspices of the Office of Scientific Intelligence (OSI), it represented a significant escalation in human experimentation aimed at countering perceived threats from communist brainwashing and enhancing U.S. intelligence capabilities. The project delved into the use of drugs, hypnosis, and other manipulative strategies to induce states of vulnerability, amnesia, and compliance in subjects, often without their consent. Its activities raised profound ethical concerns about the boundaries of psychological and physiological harassment in pursuit of national security objectives.

History and Origins

The origins of Project ARTICHOKE trace back to the immediate postwar period, amid escalating Cold War tensions. Fears of Soviet and Chinese advancements in brainwashing techniques, particularly those reportedly used on prisoners of war (POWs) during the Korean War, prompted the CIA to investigate defensive and offensive countermeasures. Initially designated as Project BLUEBIRD in 1950, the program focused on analyzing foreign activities involving drugs and psychochemicals for interrogation purposes. By August 1951, it was restructured and renamed ARTICHOKE, expanding its scope to include more aggressive operational experiments.

Directed by CIA leadership, including Director Walter Bedell Smith and Deputy Director Allen Dulles, the project evolved rapidly. Early memos emphasized the potential of augmenting traditional interrogation with hypnosis, shock, and substance dependence to exploit human vulnerabilities. Responsibility shifted from the OSI to the Office of Security in 1952, reflecting internal disputes over control and methodology. Declassified documents reveal that ARTICHOKE was part of a broader continuum of CIA efforts to master behavior control, drawing on collaborations with the Army, Navy, Air Force, and FBI through the ARTICHOKE Committee.

Objectives

At its core, Project ARTICHOKE sought to determine whether individuals could be compelled to perform actions against their will, including acts of assassination that defied fundamental instincts of self-preservation. This aligned with the “Manchurian Candidate” concept—a hypothetical scenario where a subject, through mind control, could be programmed as an unwitting assassin. The program aimed to develop special interrogation techniques for extracting information from defectors, refugees, and suspected double agents, while also exploring incapacitating agents for operational use. Broader goals included inducing amnesia induction, narcosis, and states of hypnotic regression to erase memories or implant suggestions, thereby creating reliable tools for covert operations.

The CIA’s emphasis on physiological harassment extended to studying diseases like dengue fever, not for lethality but as means to cause short- and long-term disablement, rendering targets more susceptible to manipulation. This reflected a strategic intent to control “weaker” segments of society, such as potential agents or POWs, in the face of ideological threats. Additionally, the project investigated the feasibility of creating “zombie-like” states through chemical means, where subjects could be directed remotely or conditioned for specific tasks without recollection.

Methods and Techniques

Project ARTICHOKE employed a wide array of methods, blending pharmacology, psychology, and physical coercion. Central to its arsenal were drugs such as lysergic acid diethylamide (LSD), mescaline, peyote, heroin, marijuana, and cocaine, administered to induce altered states conducive to interrogation. Techniques like forced morphine addiction followed by abrupt drug withdrawal were used to exploit substance dependence, breaking down resistance and fostering dependency on interrogators.

Hypnosis played a pivotal role, often combined with narco-hypnotism—drug-enhanced hypnotic sessions—to achieve regression therapy and hypnotic regression, where subjects were regressed to earlier mental states for vulnerability exploitation. Incapacitating agents, including barbiturates like sodium pentothal and stimulants like Desoxyn, were tested for their efficacy in producing amnesia or compliance. Physiological harassment extended to total isolation, sensory deprivation, and even electroshocks, creating environments of extreme duress to simulate and study brainwashing.

Declassified reports detail combinations of these approaches, such as using hypnosis post-narcosis to induce total amnesia through post-hypnotic suggestion, demonstrating the project’s innovative yet unethical integration of techniques. Experiments also explored polygraph manipulation under drug influence and the use of ultrasonic waves or electromagnetic fields to disrupt cognitive functions, though these were less documented and often yielded inconsistent results.

Key Personnel and Organization

Oversight of Project ARTICHOKE involved key figures like former U.S. Army Brigadier General Paul F. Gaynor, who assumed leadership amid inter-agency rivalries and managed day-to-day operations. The ARTICHOKE Committee facilitated coordination across intelligence branches, ensuring multidisciplinary input. Other notable personnel included Morse Allen, a focal point for hypnosis experiments, and Sidney Gottlieb, who later transitioned to related programs.

The program’s structure emphasized secrecy, with teams dispatched for field tests and safe houses used for domestic trials. Collaborations extended to external experts, including psychiatrists like Donald Ewen Cameron, whose work on psychic driving influenced later iterations. Internal memos highlight the involvement of pharmacologists and psychologists from academic institutions, often under classified contracts, to refine techniques and analyze outcomes.

Experiments and Subjects

Operational experiments under ARTICHOKE targeted diverse subjects, including CIA agents unknowingly dosed with LSD for extended periods (e.g., 77 days), Russian agents suspected of doubling, and foreign nationals labeled as “aliens.” POWs, defectors, refugees, and even mental patients were subjected to rigorous testing, often under the guise of medical evaluations. One documented case involved inducing regression and amnesia in suspected doubles using combined chemical-hypnotic methods, deemed “entirely successful” by handlers.

Subjects frequently emerged with fragmented memories or complete amnesia, highlighting the project’s focus on erasing traces of experimentation. Ethical lapses were evident in the non-consensual nature of these trials, which prioritized intelligence gains over human rights. Long-term effects on participants included psychological trauma, addiction issues, and in some cases, permanent cognitive impairments, underscoring the human cost of such research.

Locations and Operations

ARTICHOKE operations spanned global locales, with teams conducting tests in Europe, Japan, Southeast Asia, the Philippines, and secret facilities like those in the Canal Zone and West Germany. Southeast Asia operations were particularly active, leveraging regional conflicts for subject procurement. Domestic safe houses, managed by figures like federal narcotics agent George White, facilitated unwitting experiments on U.S. citizens.

These sites enabled “refining” of techniques in real-world settings, including brutal interrogations and field tests of incapacitating agents. Operations often involved cross-border collaborations, with agents embedded in allied intelligence services to access diverse subject pools and test environmental variables.

Connections to Other Projects

Project ARTICHOKE served as a direct precursor to Project MKULTRA, which absorbed and expanded its methodologies starting in April 1953. It built upon BLUEBIRD’s foundations and influenced subsequent initiatives like Operation Midnight Climax. Links to broader CIA efforts, such as collaborations with former Nazi scientists under Operation Paperclip, underscored the program’s roots in wartime intelligence practices. The transition to MKULTRA involved scaling up experiments, incorporating more subcontractors, and diversifying into areas like subliminal messaging and mass behavior modification.

Legacy and Declassification

Project ARTICHOKE’s legacy endures as a stark example of Cold War-era excesses in human experimentation, contributing to ongoing debates on ethics in intelligence. Declassified documents, released through FOIA requests and archived by organizations like the National Security Archive, have illuminated its operations since the 1970s. Revelations of non-consensual drugging and psychological torment prompted congressional inquiries and public apologies, though many records remain redacted or destroyed. The program’s influence persists in discussions of mind control’s feasibility and the moral costs of covert operations, informing modern policies on human subject research and surveillance ethics. It also inspired cultural depictions in literature and film, shaping public perceptions of government overreach.

They called it Artichoke. It was a war on the human mind.