Things Worth Noting
Biological immortality remains impossible due to fundamental limits in human biology. The Hayflick limit restricts normal body cells to about 50-70 divisions before they enter replicative senescence and stop dividing, acting as a built-in molecular clock. This is driven by telomere shortening—protective caps on chromosomes that erode with each cell division because of the end […]
Aging isn’t just about chronological age—your biological age reflects your body’s true health and can be influenced by epigenetics. While DNA is fixed, epigenetics acts like switches, turning genes on or off through mechanisms like DNA methylation, histone modifications, and chromatin remodeling. Lifestyle factors—diet, exercise, sleep, and stress management—can slow epigenetic drift, reduce age acceleration, […]
Telomeres, protective caps at chromosome ends, shorten with each cell division, driving aging and diseases like cardiovascular issues, neurodegeneration, and dyskeratosis congenita. Telomerase, an enzyme with hTERT and TERC components, extends telomeres, supporting longevity. Natural activators like 08AGTLF from Centella asiatica (8.8-fold boost), oleanolic acid (5.9-fold), and TA-65 from Astragalus (2.2-fold) enhance telomerase, promoting immunity […]
TA-65, derived from Astragalus membranaceus, is a telomerase activator that promotes telomere lengthening, potentially slowing aging, boosting immunity, and enhancing vitality. This plant-based supplement, with cycloastragenol as its active compound, supports cellular health by reducing oxidative stress and inflammation. Taken at 250-1000mg daily, TA-65 follows a bell-shaped dose-response curve for optimal results, often paired with […]